α-actinin Rabbit pAb
ENT-A1261
Description
| REF | ENT-A1261 |
|---|---|
| Category | Antibody Polyclonal |
| Description | α-actinin Rabbit pAb |
| Source | Rabbit |
| Applications | WB, IHC |
| Reactivity | Rat, Mouse |
| Reactivity | Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 103kDa |
| Human Gene ID | 87 |
| Human Swiss Prot Nº | P12814 |
| Subcellular Location | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane |
Other Name: actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody
Background: α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.