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WDR62 rabbit pAb

WDR62 rabbit pAb

ENT-A11452

Description

 

 

 

REF ENT-A11452
Category Antibody Polyclonal
Description WDR62 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse
Reactivity Human; Mouse
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human WDR62 AA range: 984-1034
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 284403
Human Swiss Prot Nº O43379
Subcellular Location Nucleus . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Shows cell cycle-dependent localization. Accumulates to the spindle pole during mitosis. Colocalizes with CDK5RAP2, CEP152 and WDR62 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles. .

Other Name:

Background: This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011],