Vav3 rabbit pAb
ENT-A4576
Description
| REF | ENT-A4576 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Vav3 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 98kD |
| Human Gene ID | 10451 |
| Human Swiss Prot Nº | Q9UKW4 |
| Subcellular Location | intracellular,cytosol,plasma membrane,extracellular exosome, |
Other Name: VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],