UBE4A rabbit pAb
ENT-A4017
Description
| REF | ENT-A4017 |
|---|---|
| Category | Antibody Polyclonal |
| Description | UBE4A rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from the N-terminal region of human UBE4A. |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 122kD |
| Human Gene ID | 9354 |
| Human Swiss Prot Nº | Q14139 |
| Subcellular Location | Cytoplasm . |
Other Name: UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A
Background: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn’s disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011],