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TRα rabbit pAb

TRα rabbit pAb

ENT-A7123

Description

 

 

 

REF ENT-A7123
Category Antibody Polyclonal
Description TRα rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human Thyroid Hormone Receptor alpha. AA range:10-59
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 55kD
Human Gene ID 7067
Human Swiss Prot Nº P10827
Subcellular Location Nucleus.; [Isoform Alpha-2]: Cytoplasm . Nucleus . When overexpressed found in the cytoplasm where it colocalizes with TACC1. .

Other Name: THRA; EAR7; ERBA1; NR1A1; THRA1; THRA2; Thyroid hormone receptor alpha; Nuclear receptor subfamily 1 group A member 1; V-erbA-related protein 7; EAR-7; c-erbA-1; c-erbA-alpha

Background: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],