Topo IIIα rabbit pAb
ENT-A7813
Description
| REF | ENT-A7813 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Topo IIIα rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from Topo IIIα . at AA range: 350-430 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 115kD |
| Human Gene ID | 7156 |
| Human Swiss Prot Nº | Q13472 |
| Subcellular Location | Mitochondrion matrix . |
Other Name: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha
Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],