TNF α Mouse mAb
ENT-A1546
Description
| Ref | ENT-A1546 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:50 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 17,25kDa |
| Human Gene ID | 7124 |
| Human Swiss Prot No | P01375 |
| Subcellular Location | Secreted,Cell membrane |
Background: TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions..