TMEM16A rabbit pAb
ENT-A6525
Description
| REF | ENT-A6525 |
|---|---|
| Category | Antibody Polyclonal |
| Description | TMEM16A rabbit pAb |
| Source | Rabbit |
| Applications | IF;ELISA |
| Reactivity | Human;Mouse; |
| Reactivity | Human;Mouse; |
| Dilution | Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TM16A. AA range:921-970 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 55107 |
| Human Swiss Prot Nº | Q5XXA6 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. . |
Other Name: ANO1; DOG1; ORAOV2; TAOS2; TMEM16A; Anoctamin-1; Discovered on gastrointestinal stromal tumors protein 1; Oral cancer overexpressed protein 2; Transmembrane protein 16A; Tumor-amplified and overexpressed sequence 2
Background: domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle.,