Tie-1 rabbit pAb
ENT-A7128
Description
| REF | ENT-A7128 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Tie-1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | IHC-p: 100-300.Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TIE1. AA range:851-900 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 130kD |
| Human Gene ID | 7075 |
| Human Swiss Prot Nº | P35590 |
| Subcellular Location | Cell membrane ; Single-pass type I membrane protein . |
Other Name: TIE1; TIE; Tyrosine-protein kinase receptor Tie-1
Background: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],