TH (phospho Ser8) rabbit pAb
ENT-A4497
Description
| REF | ENT-A4497 |
|---|---|
| Category | Antibody Polyclonal |
| Description | TH (phospho Ser8) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Rat |
| Reactivity | Rat |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from mouse Tyrosine Hydroxylase around the phosphorylation site of Ser8. AA range:2-51 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 62kD |
| Human Gene ID | |
| Human Swiss Prot Nº | |
| Subcellular Location |
Other Name: TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH
Background: The tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.