Syk (phospho Tyr525) rabbit pAb
ENT-A1987
Description
| REF | ENT-A1987 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Syk (phospho Tyr525) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat;Monkey |
| Reactivity | Human;Mouse;Rat;Monkey |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr525. AA range:491-540 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 72kD |
| Human Gene ID | 6850 |
| Human Swiss Prot Nº | P43405 |
| Subcellular Location | Cell membrane . Cytoplasm, cytosol . |
Other Name: SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk
Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],