Survivin Mouse mAb
ENT-A1534
Description
| Ref | ENT-A1534 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat |
| Dilution | WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 16kDa |
| Human Gene ID | 332 |
| Human Swiss Prot No | O15392 |
| Subcellular Location | Cytoplasm. Nucleus. Chromosome |
Background: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death.