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SSR5 rabbit pAb

SSR5 rabbit pAb

ENT-A10742

Description

 

 

 

REF ENT-A10742
Category Antibody Polyclonal
Description SSR5 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from human protein . at AA range: 270-350
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 40kD
Human Gene ID 6755
Human Swiss Prot Nº P35346
Subcellular Location Cell membrane; Multi-pass membrane protein.

Other Name:

Background: Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010],