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SRGP2 rabbit pAb

SRGP2 rabbit pAb

ENT-A11849

Description

 

 

 

REF ENT-A11849
Category Antibody Polyclonal
Description SRGP2 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse;Rat
Reactivity Human; Mouse;Rat
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human SRGP2 AA range: 476-526
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 23380
Human Swiss Prot Nº O75044
Subcellular Location Cell membrane . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Cell junction, synapse, postsynaptic cell membrane . Cell projection, lamellipodium . Cytoplasmic vesicle, phagosome . Nucleus . Cytoplasm, cytosol . Recruited to actin-rich phagosomes during phagocytosis (By similarity). Translocates from nucleus to cytoplasm during development (By similarity). .

Other Name:

Background: This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014],