SRC-1 (Phospho Thr1179) rabbit pAb
ENT-A15706
Description
| REF | ENT-A15706 |
|---|---|
| Category | Antibody Polyclonal |
| Description | SRC-1 (Phospho Thr1179) rabbit pAb |
| Source | Rabbit |
| Applications | WB; ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human SRC-1 (Phospho Thr1179) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 158kD |
| Human Gene ID | 8648 |
| Human Swiss Prot Nº | Q15788 |
| Subcellular Location | Nucleus . |
Other Name: Nuclear receptor coactivator 1 (NCoA-1;EC 2.3.1.48;Class E basic helix-loop-helix protein 74;bHLHe74;Protein Hin-2;RIP160;Renal carcinoma antigen NY-REN-52;Steroid receptor coactivator 1;SRC-1)
Background: The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],