SNM1B rabbit pAb
ENT-A4002
Description
| REF | ENT-A4002 |
|---|---|
| Category | Antibody Polyclonal |
| Description | SNM1B rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA;IHC |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen | Synthesized peptide derived from the C-terminal region of human SNM1B. |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 60kD |
| Human Gene ID | 64858 |
| Human Swiss Prot Nº | Q9H816 |
| Subcellular Location | Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome. |
Other Name: DCLRE1B; SNM1B; 5′ exonuclease Apollo; DNA cross-link repair 1B protein; SNM1 homolog B; SNMIB; hSNM1B
Background: DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008],