SNF8 rabbit pAb
ENT-A11913
Description
| REF | ENT-A11913 |
|---|---|
| Category | Antibody Polyclonal |
| Description | SNF8 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human; Mouse;Rat |
| Reactivity | Human; Mouse;Rat |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | Synthesized peptide derived from human SNF8 AA range: 78-128 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 11267 |
| Human Swiss Prot Nº | Q96H20 |
| Subcellular Location | Cytoplasm. Endosome membrane. Nucleus . Late endosome membrane. Recruited to the endosome membrane to participate in vesicle formation. |
Other Name:
Background: The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],