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SMCA5 rabbit pAb

SMCA5 rabbit pAb

ENT-A11921

Description

 

 

 

REF ENT-A11921
Category Antibody Polyclonal
Description SMCA5 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse
Reactivity Human; Mouse
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human SMCA5 AA range: 851-901
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 8467
Human Swiss Prot Nº O60264
Subcellular Location Nucleus . Chromosome . Localizes to mitotic chromosomes (PubMed:12972596). Co-localizes with RSF1 in the nucleus (PubMed:12972596). Co-localizes with PCNA at replication foci during S phase (PubMed:15543136). Co-localizes with BAZ1B/WSTF at replication foci during late-S phase (PubMed:15543136). Recruited to DNA damage sites following interactiuon with SIRT6 (PubMed:23911928). .

Other Name:

Background: The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008],