SKAP1 rabbit pAb
ENT-A10219
Description
| REF | ENT-A10219 |
|---|---|
| Category | Antibody Polyclonal |
| Description | SKAP1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 39kD |
| Human Gene ID | 8631 |
| Human Swiss Prot Nº | Q86WV1 |
| Subcellular Location | Cytoplasm . Nucleus . Cell membrane . Upon T-cell stimulation, translocates to lipid rafts at the cell membrane. . |
Other Name:
Background: This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008],