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SgK269 rabbit pAb

SgK269 rabbit pAb

ENT-A7305

Description

 

 

 

REF ENT-A7305
Category Antibody Polyclonal
Description SgK269 rabbit pAb
Source Rabbit
Applications WB;IHC
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000;IHC-p 1:50-300
Immunogen The antiserum was produced against synthesized peptide derived from human SGK269. AA range:111-160
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 195kD
Human Gene ID 79834
Human Swiss Prot Nº Q9H792
Subcellular Location Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Colocalizes with F-actin in serum-rich medium (PubMed:20534451). Actin colocalization is reduced during serum starvation (PubMed:20534451). .

Other Name: PEAK1; KIAA2002; Pseudopodium-enriched atypical kinase 1; Sugen kinase 269; Tyrosine-protein kinase SgK269

Background: This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014],