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Septin 8 rabbit pAb

Septin 8 rabbit pAb

ENT-A3677

Description

 

 

 

REF ENT-A3677
Category Antibody Polyclonal
Description Septin 8 rabbit pAb
Source Rabbit
Applications WB;ELISA;IHC
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen The antiserum was produced against synthesized peptide derived from human SEPT8. AA range:170-219
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 50kD
Human Gene ID 23176
Human Swiss Prot Nº Q92599
Subcellular Location Cytoplasm . Cytoplasm, cytoskeleton . Cell junction, synapse . Cell projection, axon . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Cell junction, synapse, presynapse . Expressed in axons of immature neurons, localizes to synapses in mature neurons (By similarity). In platelets, found in areas surrounding alpha-granules (PubMed:15116257). .

Other Name: SEPT8; KIAA0202; Septin-8

Background: septin 8(SEPT8) Homo sapiens This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],