SEC61B Rabbit pAb
ENT-A12003
Description
| REF | ENT-A12003 |
|---|---|
| Category | Antibody Polyclonal |
| Description | SEC61B Rabbit pAb |
| Source | Rabbit |
| Applications | IHC; ELISA |
| Reactivity | Human; Mouse; Rat |
| Reactivity | Human; Mouse; Rat |
| Dilution | IHC-p 1:50-200, ELISA(peptide)1:5000-20000 |
| Immunogen | Synthesized peptide derived from human SEC61B AA range: 30-110 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 10952 |
| Human Swiss Prot Nº | P60468 |
| Subcellular Location | Endoplasmic reticulum membrane ; Single-pass membrane protein . |
Other Name: Protein transport protein Sec61 subunit beta
Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008],