SCP-3 rabbit pAb
ENT-A4051
Description
| REF | ENT-A4051 |
|---|---|
| Category | Antibody Polyclonal |
| Description | SCP-3 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA;IHC |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen | Synthesized peptide derived from the Internal region of human SCP-3. |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 27kD |
| Human Gene ID | 50511 |
| Human Swiss Prot Nº | Q8IZU3 |
| Subcellular Location | Nucleus . Chromosome . Chromosome, centromere . It is present in early unpaired cores, in the lateral domains of the synaptonemal complex and in the chromosome cores when they separate at diplotene. It is found axial to the metaphase I chromosomes and in association with pairs of sister centromeres. The centromere-associated protein becomes dissociated from the centromeres at anaphase II and is not found in mitotic metaphase centromeres. . |
Other Name: SYCP3; SCP3; Synaptonemal complex protein 3; SCP-3
Background: This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010],