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Scn4b rabbit pAb

Scn4b rabbit pAb

ENT-A3664

Description

 

 

 

REF ENT-A3664
Category Antibody Polyclonal
Description Scn4b rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human SCN4B. AA range:61-110
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 27kD
Human Gene ID 6330
Human Swiss Prot Nº Q8IWT1
Subcellular Location Cell membrane ; Single-pass type I membrane protein .

Other Name: SCN4B; Sodium channel subunit beta-4

Background: The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009],