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S7A14 rabbit pAb

S7A14 rabbit pAb

ENT-A12043

Description

 

 

 

REF ENT-A12043
Category Antibody Polyclonal
Description S7A14 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse
Reactivity Human; Mouse
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human S7A14 AA range: 50-100
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 85kD
Human Gene ID 57709
Human Swiss Prot Nº Q8TBB6
Subcellular Location Lysosome membrane ; Multi-pass membrane protein . Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes.

Other Name: Probable cationic amino acid transporter (Solute carrier family 7 member 14)

Background: This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014],