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S100 rabbit pAb

S100 rabbit pAb

ENT-A15958

Description

 

 

 

REF ENT-A15958
Category Antibody Polyclonal
Description S100 rabbit pAb
Source Rabbit
Applications WB;IHC;IF
Reactivity Human;Rat;Mouse
Reactivity Human;Rat;Mouse
Dilution Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen Recombinant Protein of S100
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 15kD
Human Gene ID 6271
Human Swiss Prot Nº P23297
Subcellular Location Cytoplasm . Sarcoplasmic reticulum . Mitochondrion .

Other Name: Protein S100-A1 (S-100 protein alpha chain;S-100 protein subunit alpha;S100 calcium-binding protein A1)

Background: S100 calcium binding protein A1(S100A1) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008],