RN213 rabbit pAb
ENT-A12147
Description
| REF | ENT-A12147 |
|---|---|
| Category | Antibody Polyclonal |
| Description | RN213 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | IHC-p 1：50-200 |
| Immunogen | Synthesized peptide derived from human RN213. AA range:307-407 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 57674 |
| Human Swiss Prot Nº | Q63HN8 |
| Subcellular Location | Cytoplasm, cytosol . Lipid droplet . |
Other Name:
Background: This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],