RIF1 rabbit pAb
ENT-A15113
Description
| REF | ENT-A15113 |
|---|---|
| Category | Antibody Polyclonal |
| Description | RIF1 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:1000-2000 |
| Immunogen | Synthesized peptide derived from human RIF1 AA range: 1428-1478 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 55183 |
| Human Swiss Prot Nº | Q5UIP0 |
| Subcellular Location | Nucleus . Chromosome . Chromosome, telomere . Cytoplasm, cytoskeleton, spindle . Following interaction with TP53BP1, recruited to sites of DNA damage, such as DSBs (By similarity). Exhibits ATM- and TP53BP1-dependent localization to uncapped or aberrant telomeres and to DNA double strand breaks (DSBs) (PubMed:15342490). Does not associate with normal telomere structures (PubMed:15342490, PubMed:15583028). Localizes to microtubules of the midzone of the mitotic spindle during anaphase, and to condensed chromosomes in telophase (PubMed:15583028). . |
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