RFA1 rabbit pAb
ENT-A15888
Description
| REF | ENT-A15888 |
|---|---|
| Category | Antibody Polyclonal |
| Description | RFA1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA;IHC |
| Reactivity | Human;Monkey;Mouse;Rat |
| Reactivity | Human;Monkey;Mouse;Rat |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen | Synthesized peptide derived from human RFA1 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 6117 |
| Human Swiss Prot Nº | P27694 |
| Subcellular Location | Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. . |
Other Name: Replication protein A 70 kDa DNA-binding subunit (RP-A p70;Replication factor A protein 1;RF-A protein 1;Single-stranded DNA-binding protein)
Background: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,