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Recombinant Human FGL1 (C-6His)

Recombinant Human FGL1 (C-6His)

Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a 6His tag at the C-terminus.

Description

Reference ESCIT232
Size 50ug
Molecular Weight 35 KDa
Purity Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Biological Activity

Other names: Fibrinogen-like protein 1; FGL1; HP-041; HESCIassocin; HFRESCI-1; LFIRE-1

Redissolve:

Storage: Store at ?-70°C, stable for 6 months after receipt.
Store at ?-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.

Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, HESCIassocin, HFRESCI-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hESCIatocytes. HESCIassocin may play a role in the development of hESCIatocellular carcinomas. HESCIassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is rESCIorted that it is a major immune inhibitory ligand of LAG-3 .