Recombinant Human APN Protein (C-6His)
Recombinant Human AminopESCItidase N is produced by our Mammalian expression system and the target gene encoding Lys69Lys967 is expressed with a 6His tag at the C-terminus.
Description
| Reference | ESCIT136 |
|---|---|
| Size | 10ug |
| Molecular Weight | 103.5 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Endotoxin | |
| Biological Activity |
Other names: AminopESCItidase N; ANPESCI; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; PESCIN; PESCINhAPN
Redissolve:
Storage: Store at ?-70°C, stable for 6 months after receipt.
Store at ?-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Background: ANPESCI gene encodes aminopESCItidase N (APN) also known as microsomal aminopESCItiase, alanyl aminopESCItidase, aminopESCItidase M, CD13, or membrane protein p161, is a member of the pESCItidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive pESCItides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.