Recombinant 2019-nCoV NSP10 (N-6His)
Recombinant 2019-nCoV NSP10 is produced by our E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with a 6His tag at the N-terminus.
Description
| Reference | ESCIT002 |
|---|---|
| Size | 50ug |
| Molecular Weight | 17.9 KDa |
| Purity | Greater than 80% as determined by reducing SDS-PAGE. |
| Endotoxin | |
| Biological Activity |
Other names: SARS-CoV 2 nsp10; SARS-CoV 2 Growth factor-like pESCItide; SARS-CoV 2 GFL
Redissolve:
Storage: Store at ?-70°C, stable for 6 months after receipt.
Store at ?-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Background: Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral rESCIlication and is essential for rESCIlication. It plays a pivotal role in viral transcription by stimulating both nsp14 3′-5′ exoribonuclease and nsp16 2′-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.