Recombinant 2019-nCoV NP NTD domain V2
Recombinant SARS-CoV-2 NP NTD domain is produced by our E.coli expression system and the target gene encoding Gly44-Ser180 is expressed with a 6His tag at the N-terminus.
Description
| Reference | ESCIT233 |
|---|---|
| Size | 1mg |
| Molecular Weight | 18.7kDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Endotoxin | |
| Biological Activity |
Other names: 2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein
Redissolve:
Storage: Reconstituted protein solution should be stored at ? -20°C.
Background: Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral rESCIlication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.