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PSCA rabbit pAb

PSCA rabbit pAb

ENT-A3538

Description

 

 

 

REF ENT-A3538
Category Antibody Polyclonal
Description PSCA rabbit pAb
Source Rabbit
Applications WB;ELISA;IHC
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen The antiserum was produced against synthesized peptide derived from human Prostate Stem Cell Antigen. AA range:41-90
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 29kD
Human Gene ID 8000
Human Swiss Prot Nº O43653
Subcellular Location Cell membrane ; Lipid-anchor, GPI-anchor .

Other Name: PSCA; Prostate stem cell antigen

Background: This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],