PR48 rabbit pAb
ENT-A5556
Description
| REF | ENT-A5556 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PR48 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PPP2R3B. AA range:364-413 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 70kD |
| Human Gene ID | 28227 |
| Human Swiss Prot Nº | Q9Y5P8 |
| Subcellular Location | Nucleus . |
Other Name: PPP2R3B; PPP2R3L; Serine/threonine-protein phosphatase 2A regulatory subunit B” subunit beta; PP2A subunit B isoform PR48; Protein phosphatase 2A 48 kDa regulatory subunit
Background: Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B’/PR61, and B”/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B” family. The B” family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B”. [provided by RefSeq, Apr 2010],