PLCD3 rabbit pAb
ENT-A12374
Description
| REF | ENT-A12374 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PLCD3 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | Synthesized peptide derived from human PLCD3 AA range: 501-551 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 113026 |
| Human Swiss Prot Nº | Q8N3E9 |
| Subcellular Location | Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow . Localizes at the cleavage furrow during cytokinesis. . |
Other Name:
Background: This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008],