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PIG-X rabbit pAb

PIG-X rabbit pAb

ENT-A3486

Description

 

 

 

REF ENT-A3486
Category Antibody Polyclonal
Description PIG-X rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human PIGX. AA range:183-232
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 26kD
Human Gene ID 54965
Human Swiss Prot Nº Q8TBF5
Subcellular Location Endoplasmic reticulum membrane ; Single-pass type I membrane protein .

Other Name: PIGX; Phosphatidylinositol-glycan biosynthesis class X protein; PIG-X

Background: This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],