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pICln rabbit pAb

pICln rabbit pAb

ENT-A3483

Description

 

 

 

REF ENT-A3483
Category Antibody Polyclonal
Description pICln rabbit pAb
Source Rabbit
Applications WB;ELISA;IHC
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen The antiserum was produced against synthesized peptide derived from human CLNS1A. AA range:184-233
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 37kD
Human Gene ID 1207
Human Swiss Prot Nº P54105
Subcellular Location Cytoplasm, cytosol . Nucleus . Cytoplasm, cytoskeleton . A small fraction is also associated with the cytoskeleton (PubMed:18984161).

Other Name: CLNS1A; CLCI; ICLN; Methylosome subunit pICln; Chloride channel; nucleotide sensitive 1A; Chloride conductance regulatory protein ICln; I(Cln); Chloride ion current inducer protein; ClCI; Reticulocyte pICln

Background: This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015],