PDLI3 rabbit pAb
ENT-A12425
Description
| REF | ENT-A12425 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PDLI3 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human; Mouse;Rat |
| Reactivity | Human; Mouse;Rat |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | Synthesized peptide derived from human PDLI3 AA range: 251-301 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 27295 |
| Human Swiss Prot Nº | Q53GG5 |
| Subcellular Location | Cytoplasm, myofibril, sarcomere, Z line . Localizes to myofiber Z-lines. |
Other Name:
Background: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012],