PDE4B rabbit pAb
ENT-A12432
Description
| REF | ENT-A12432 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PDE4B rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Rat |
| Reactivity | Human;Rat |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human PDE4B AA range: 103-153 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 5142 |
| Human Swiss Prot Nº | Q07343 |
| Subcellular Location | [Isoform PDE4B5]: Cytoplasm . Cell membrane . |
Other Name:
Background: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],