PDE10A rabbit pAb
ENT-A4658
Description
| REF | ENT-A4658 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PDE10A rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA;IHC |
| Reactivity | Human;Rat |
| Reactivity | Human;Rat |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PDE10A. AA range:21-70 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 75kD |
| Human Gene ID | 10846 |
| Human Swiss Prot Nº | Q9Y233 |
| Subcellular Location | Cytoplasm, cytosol . |
Other Name: PDE10A; cAMP and cAMP-inhibited cGMP 3′; 5′-cyclic phosphodiesterase 10A
Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5′ monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011],