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Paxillin rabbit pAb

Paxillin rabbit pAb

ENT-A6750

Description

 

 

 

REF ENT-A6750
Category Antibody Polyclonal
Description Paxillin rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human Paxillin. AA range:144-193
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 65kD
Human Gene ID 5829
Human Swiss Prot Nº P49023
Subcellular Location Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Cytoplasm, cell cortex . Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389). .

Other Name: PXN; Paxillin

Background: This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011],