Parafibromin rabbit pAb
ENT-A8186
Description
| REF | ENT-A8186 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Parafibromin rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen | Synthesized peptide derived from human Parafibromin. at AA range: 51-100 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 60kD |
| Human Gene ID | 79577 |
| Human Swiss Prot Nº | Q6P1J9 |
| Subcellular Location | Nucleus . |
Other Name: Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)
Background: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3′ mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009],