Palladin rabbit pAb
ENT-A5302
Description
| REF | ENT-A5302 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Palladin rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from Palladin . at AA range: 450-530 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 150kD |
| Human Gene ID | 23022 |
| Human Swiss Prot Nº | Q8WX93 |
| Subcellular Location | Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Cytoplasm, myofibril, sarcomere, Z line . Cell projection, ruffle . Cell projection, podosome . Cell projection, lamellipodium . Cell projection, axon . Cell projection, growth cone . Localizes to stress fibers and Z lines (PubMed:11598191, PubMed:16125169, PubMed:17322171, PubMed:17537434). Preferentially expressed in the excitatory presynaptic terminals (By similarity). . |
Other Name: PALLD; KIAA0992; CGI-151; Palladin; SIH002; Sarcoma antigen NY-SAR-77
Background: This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],