P53 Rabbit pAb
ENT-A1215
Description
| REF | ENT-A1215 |
|---|---|
| Category | Antibody Polyclonal |
| Description | P53 Rabbit pAb |
| Source | Rabbit |
| Applications | WB, IHC |
| Reactivity | Rat, Mouse |
| Reactivity | Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:500-1,000 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 53kDa |
| Human Gene ID | 7157 |
| Human Swiss Prot Nº | P04637 |
| Subcellular Location | Cytoplasm, Cytoplasm, Nucleus |
Other Name: Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody
Background: p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.