p53 Mouse mAb
ENT-A1432
Description
| Ref | ENT-A1432 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53 |
| Application | WB, IHC, IF |
| Source | Mouse |
| Reactivity | Human |
| Dilution | WB 1:2,000 IHC 1:200 IF 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 53kDa |
| Human Gene ID | 7157 |
| Human Swiss Prot No | P04637 |
| Subcellular Location | Cytoplasm; Cytoplasm. Nucleus |
Background: p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.