P38 (1G1) Mouse mAb
ENT-A1617
Description
| Ref | ENT-A1617 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | MAP kinase p38 alpha, p38 MAP kinase, CSBP , RK, MAPK 14 antibody |
| Application | IHC |
| Source | Mouse |
| Reactivity | Human, Mouse, Rat |
| Dilution | IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 42kDa |
| Human Gene ID | 1432 |
| Human Swiss Prot No | Q16539 |
| Subcellular Location | Cytoplasm,Nucleus |
Background: p38 MAP kinase (MAPK) is the mammalian orthologue of the yeast HOG kinase that participates in a signaling cascade controlling cellular responses to cytokines and stress. Isoforms p38α, β, γ and δ have been identified. p38 MAPK is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharide (LPS), UV light, and growth factors.