OTUD2 rabbit pAb
ENT-A3395
Description
| REF | ENT-A3395 |
|---|---|
| Category | Antibody Polyclonal |
| Description | OTUD2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human YOD1. AA range:116-165 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 35kD |
| Human Gene ID | 55432 |
| Human Swiss Prot Nº | Q5VVQ6 |
| Subcellular Location | Cytoplasm . Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains. . |
Other Name: YOD1; DUBA8; HIN7; OTUD2; Ubiquitin thioesterase OTU1; DUBA-8; HIV-1-induced protease 7; HIN-7; HsHIN7; OTU domain-containing protein 2
Background: Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],