OTOG rabbit pAb
ENT-A12513
Description
| REF | ENT-A12513 |
|---|---|
| Category | Antibody Polyclonal |
| Description | OTOG rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | IHC-p 1：50-200 |
| Immunogen | Synthesized peptide derived from human OTOG AA range: 2706-2756 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 340990 |
| Human Swiss Prot Nº | Q6ZRI0 |
| Subcellular Location | Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Secreted, extracellular space . Found in fiber-like structures during the maturation process of the tectorial membrane. . |
Other Name:
Background: The protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization, the anchoring of otoconial membranes and cupulae to the neuroepithelia, and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness, type 18B. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014],