OTOAN rabbit pAb
ENT-A12514
Description
| REF | ENT-A12514 |
|---|---|
| Category | Antibody Polyclonal |
| Description | OTOAN rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human OTOAN AA range: 1044-1094 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 146183 |
| Human Swiss Prot Nº | Q7RTW8 |
| Subcellular Location | Apical cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side . Secreted, extracellular space, extracellular matrix . At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes. . |
Other Name:
Background: The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],